A literature search was conducted using the PubMed and Embase databases to collect clinical trials related to IgA nephropathy conducted before November 18, 2022. The search keywords included IgAN and drug names.

A total of 40 studies with 83 treatment arms and 2288 subjects were included in the analysis.The included studies were classified into 6 classes with different pharmacological mechanisms according to the classification criteria of the clinical trial summary in the evidence-based clinical practice guidelines for IgA nephropathy published in 2014.