Literature Overview

To compare the efficacy of different inhaled corticosteroids drugs in the treatment of childhood asthma, a literature search was conducted using the PubMed and Embase databases to collect RCTs related with a deadline of Mar 2, 2022. The search keywords included Budesonide, Ciclesonide, Fluticasone furoate, Fluticasone propionate and Mometasone furoate. The endpoint for this study were forced expiratory volume in the first second (FEV1). A total of 6 studies with 16 treatment arms and 2237 subjects were included in the analysis.

*Model analysis only including budesonide, ciclesonide and fluticasone furoate